UGM Team Finds Mutated Corona Virus in Jogja! Transmissibility 10 Times

25, JOGJA–Coronavirus is said to have mutated in the DIY and Central Java regions. In the Special Region of Yogyakarta (DIY) and Central Java (Central Java) a D614G mutation of the SARS-CoV-2 corona virus was detected.

The findings were revealed after the Genetic Working Group of the Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada (FK-KMK UGM) and the team managed to identify the Whole Genome Sequencing (WGS) of four isolates from Yogyakarta and Central Java, which have been published in GISAID.

Three of the four isolates contained the D614G mutation.

Chairperson of the Genetic Working Group FK-KMK UGM, Dr. Gunadi, revealed that the D614G mutation in the SARS-CoV-2 virus had an infectious power 10 times higher.

The D614G mutation, said Dr. Gunadi, had spread to almost all corners of the world, namely 77.5% of the total 92,090 isolates containing the D614G mutation.

He added that in Indonesia alone, nine out of 24 isolates published in GISAID had been reported to contain the D614G mutation.

“One-third were detected in Yogyakarta and Central Java,” said Dr. Gunadi, Tuesday (1/9/2020).

Doctor Gunadi admitted that data from Indonesia is still far from ideal compared to world data for the benefit of data on the spread of the virus in the population (epidemiology) and the development of vaccines and / or COVID-19 therapies in the world, especially in Indonesia.

Even so, he continued, with the fact that the D614G mutation of the SARS-CoV-2 virus was detected in Indonesia, all parties should be more disciplined in implementing health protocols, such as washing hands, wearing masks, avoiding crowds, and so on.

To date, the total population infected with COVID-19 worldwide is 25,590,934 cases, with a death rate of 853,415 cases.

Meanwhile in Indonesia itself, since the announcement of the first COVID-19 patient in March 2020, as of August 31, 2020 there were 174,796 cases of COVID-19 with 7,417 patients dying.

The case data makes Indonesia rank 23 with the most patients in the world.

On the other hand, unfortunately the SARS-CoV-2 WGS data from Indonesia published on GISAID is very minimal, namely 24 full-genomes compared to 92,090 full-genomes from around the world (1 September 2020).

In fact, WGS data is very important to know the epidemiology (spread) of the virus, including the type of mutation (clade) in the community, its relationship with the severity of COVID-19 patients, development of vaccines and / or therapy for COVID-19 in the future, especially in Indonesia.

“So, WGS data from Indonesian isolates is a necessity and a form of independence for the Indonesian national identity,” said Dr. Gunadi.


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